• Association between Alcohol Consumption and Body Composition in Russian Adults and Patients Treated for Alcohol-Related Disorders: The Know Your Heart Cross-Sectional Study 

      Mitkin, Nikita Andreevich; Unguryanu, Tatiana Nikolaevna; Malyutina, Sofia; Kudryavtsev, Alexander V (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-07)
      There is conflicting evidence about the association between alcohol consumption and body composition (BC). We aimed to investigate this association in Russian adults. The study population included 2357 residents of Arkhangelsk aged 35–69 years, and 272 in-patients treated for alcohol problems (narcological patients) who participated in the Know Your Heart (KYH) cross-sectional study in 2015–2017. ...
    • Association between atmospheric air temperature and blood pressure among adult population in different seasons 

      Rastokina, Tatiana N.; Kudryavtsev, Alexander V; Unguryanu, Tatiana Nikolaevna (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-17)
      BACKGROUND: The prevalence of hypertension in the Arkhangelsk region is steadily increasing. Despite the progress in the diagnostics and the availability of treatment, a half of the population are unaware of their hypertension and its potential consequences, and consequently, do not adhere to the prescribed medications. This lack of awareness, coupled with the challenging climatic conditions of the ...
    • The Association between Kidney Function Biomarkers and Delayed Memory Impairments among Older Adults in the European North of Russia 

      Poskotinova, Liliya; Kontsevaya, Anna; Kudryavtsev, Alexander V (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-30)
      The prevention of memory decline requires better knowledge of biological markers. We studied the associations between kidney function biomarkers and memory decline (assessed with the Mini-Mental State Examination—MMSE) in elderly individuals without dementia (MMSE 24–30, age 60–74 years, n = 643, Arkhangelsk, Russia). Participants were divided by sex and into three groups according to the delayed ...
    • Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. 

      Cook, Sarah; Eggen, Anne Elise; Hopstock, Laila Arnesdatter; Malyutina, S; Shapkina, M; Kudryavtsev, Alexander V; Melbye, Hasse; Quint, JK (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-14)
      Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Despite a high prevalence of smoking and respiratory symptoms, two recent population-based studies in Russia found a relatively low prevalence of obstructive lung function. Here, we investigated the prevalence of both obstructive lung disease and respiratory symptoms in a population-based ...
    • Comparing prevalence of chronic kidney disease and its risk factors between population-based surveys in Russia and Norway 

      Cook, Sarah; Solbu, Marit Dahl; Eggen, Anne Elise; Iakunchykova, Olena; Averina, Maria; Hopstock, Laila Arnesdatter; Kholmatova, Kamila Kahramonzhonovna; Kudryavtsev, Alexander V; Leon, David A.; Malyutina, Sofia; Ryabikov, Andrew; Williamson, Elizabeth; Nitsch, Dorothea (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-14)
      Background - Little data exists on the prevalence of chronic kidney disease (CKD) in the Russian population. We aimed to estimate the prevalence of CKD in a population-based study in Russia, compare with a similar study in Norway, and investigate whether differences in risk factors explained between-study differences in CKD.<p> <p>Methods - We compared age- and sex-standardised prevalence of ...
    • COVID-19: seroprevalence and adherence to preventive measures in Arkhangelsk, Northwest Russia 

      Krieger, Ekaterina Anatoljevna; Sharashova, Ekaterina; Kudryavtsev, Alexander V; Samodova, Olga; Kontsevaya, Anna; Brenn, Tormod; Postoev, Vitaly (Journal article; Tidsskriftartikkel, 2023-03-15)
      Background - The published estimates of SARS-CoV-2 seroprevalence in Russia are few. The study aimed to assess the SARS-CoV-2 seroprevalence in Arkhangelsk (Northwest Russia), in a year after the start of the pandemic, to evaluate the population adherence to non-pharmaceutical interventions (NPIs), and to investigate characteristics associated with COVID-19 seropositive status.<p> <p>Methods - ...
    • Effect of adiposity on differences in carotid plaque burden in studies conducted in Norway and Russia: a cross-sectional analysis of two populations at very different risk of cardiovascular mortality 

      Imahori, Yume; Frost, Chris; Mathiesen, Ellisiv B.; Ryabikov, Andrey; Kudryavtsev, Alexander V; Malyutina, Sofia; Kornev, Michael; Hughes, Alun D; Hopstock, Laila Arnesdatter; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-06)
      <i>Objectives</i> - Large differences exist in the burden of cardiovascular disease (CVD) between Russia and Western European countries including Norway. Obesity prevalence may contribute to the differences. We investigated whether difference in the level of adiposity, assessed using body mass index and waist-to-hip ratio(WHR), could explain intercountry differences in the burden of carotid plaque, ...
    • Evidence for a direct harmful effect of alcohol on myocardial health: A large cross-sectional study of consumption patterns and cardiovascular disease risk biomarkers from northwest Russia, 2015 to 2017 

      Iakunchykova, Olena; Averina, Maria; Kudryavtsev, Alexander V; Wilsgaard, Tom; Soloviev, Andrey; Schirmer, Henrik; Cook, Sarah Anne; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-18)
      <i>Background</i> - Alcohol drinking is an increasingly recognized risk factor for cardiovascular disease. However, there are few studies of the impact of harmful and hazardous drinking on biomarkers of myocardial health. We conducted a study in Russia to investigate the impact of heavy drinking on biomarkers of cardiac damage and inflammation.<p><p> <i>Methods and Results</i> - The Know Your ...
    • External validation of a deep learning electrocardiogram algorithm to detect ventricular dysfunction 

      Attia, Itzhak Zachi; Tseng, Andrew S.; Benavente, Ernest Diez; Medina-Inojosa, Jose R.; Clark, Taane; Malyutina, Sofia; Kapa, Suraj; Schirmer, Henrik; Kudryavtsev, Alexander V; Noseworthy, Peter A.; Carter, Rickey E.; Ryabikov, Andrey; Perel, Pablo; Friedman, Paul A.; Leon, David A.; Lopez-Jimenez, Francisco (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-02)
      Objective - To validate a novel artificial-intelligence electrocardiogram algorithm (AI-ECG) to detect left ventricular systolic dysfunction (LVSD) in an external population.<p> <p>Background - LVSD, even when asymptomatic, confers increased morbidity and mortality. We recently derived AI-ECG to detect LVSD using ECGs based on a large sample of patients treated at the Mayo Clinic.<p> <p>Methods ...
    • Hazardous alcohol consumption and problem drinking in Norwegian and Russian women and men: The Tromsø Study 2015–2016 and the Know Your Heart study 2015–2018 

      Hopstock, Laila Arnesdatter; Kudryavtsev, Alexander V; Malyutina, Sofia; Cook, Sarah (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-30)
      Aim: Harmful use of alcohol is a worldwide public health concern. Cultural differences may affect responses to questions on alcohol problems, making international comparisons difficult. We aimed to compare self-reported alcohol consumption and problem drinking between Norwegian and Russian populations.<p> <p>Methods: We used data from women and men aged 40–69 years participating in the Tromsø ...
    • Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function 

      Iakunchykova, Olena; Schirmer, Henrik; Leong, Darryl; Malyutina, Sofia; Ryabikov, Andrey; Averina, Maria; Kudryavtsev, Alexander V; Kornev, Mikhail; Voronina, Ekaterina; Paramonov, Andrey; Wilsgaard, Tom; Leon, David A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-02)
      Objective - The aim of the study is to assess changes in heart structure and function associated with heavy alcohol use by comparing echocardiographic indices in a population-based sample to those in patients admitted to an inpatient facility with severe alcohol problems.<p> <p>Methods and results - We used data from the Know Your Heart study (2015–2017) which is a cross-sectional study that ...
    • Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate 

      Kornev, Mikhail; Hatice, Akay Caglayan; Kudryavtsev, Alexander V; Malyutina, Sofia; Ryabikov, Andrew; Schirmer, Henrik; Rösner, Assami (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-22)
      Background - Left ventricular (LV) systolic and diastolic functions are important cardiovascular risk predictors in patients with hypertension. However, data on segmental, layer-specific strain, and diastolic strain rates in these patients are limited. The aim of this study was to investigate segmental two-dimensional strain rate imaging (SRI)-derived parameters to characterize LV systolic and ...
    • Long-term trends in blood pressure and hypertension in Russia: an analysis of data from 14 health surveys conducted in 1975–2017 

      Churilova, Elena; Shkolnikov, Vladimir M.; Shalnova, Svetlana A.; Kudryavtsev, Alexander V; Malyutina, Sofia; Nilssen, Odd-Ragnar; Laatikainen, Tiina; Leon, David A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      Background - Hypertension is recognized as an important contributor to high cardiovascular mortality in Russia. A comprehensive analysis of data from Russian studies that measured blood pressure in population-based samples has not been previously undertaken. This study aims to identify trends and patterns in mean blood pressure and the prevalence of hypertension in Russia over the most recent ...
    • Mechanisms of accidental fall injuries and involved injury factors: a registry-based study 

      Unguryanu, Tatiana Nikolaevna; Grjibovski, Andrej; Trovik, Tordis A; Ytterstad, Børge; Kudryavtsev, Alexander V (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-16)
      <p><i>Background - </i>Falls are the leading cause of injury-related morbidity and mortality worldwide, but fall injury circumstances differ by age. We studied the circumstances of accidental fall injuries by age in Shenkursk District, Northwest Russia, using the data from the population-based Shenkursk Injury Registry. <p><i>Methods -</i>Data on accidental fall injuries (hereafter: fall injuries) ...
    • Mobile app as a tool to collect health data: a survey on vaccination against COVID-19 

      Krieger, E.A.; Kudryavtsev, Alexander V; Samodova, O.V.; Bashkirev, D.S.; Mitkin, N.A.; Kontsevaya, A.V.; Postoev, V.A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      Objective. To evaluate the feasibility of using a mobile app to collect health-related data and the impact of this data collection method on the results obtained, using the COVID-19 vaccination attitude assessment as an example. Material and methods. A survey was conducted on attitudes towards COVID-19 vaccination using the «Know Your Heart» mobile app. A total of 1,770 Arkhangelsk region residents ...
    • Novel approach to artefact detection and the definition of normal ranges of segmental strain and strain-rate values 

      Kornev, Mikhail; Caglayan, Hatice Aklay; Kudryavtsev, Alexander V; Malyutina, Sofia; Ryabikov, Andrew; Stylidis, Michael; Schirmer, Henrik; Rosner, Assami (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-13)
      Aims - Strain artefacts are known to hamper the correct interpretation of segmental strain and strain-rate (S/SR). Defining the normal ranges of myocardial segmental deformation is important in clinical studies and routine echocardiographic practice. In order to define artefact-free normal ranges for segmental longitudinal S/SR parameters, we investigated the extent to which different types of ...
    • Obesity Prevalence and Associated Socio-Demographic Characteristics and Health Behaviors in Russia and Norway 

      Kholmatova, Kamila Kahramonzhonovna; Krettek, Alexandra; Leon, David A; Malyutina, Sofia; Cook, Sarah; Hopstock, Laila Arnesdatter; Løvsletten, Ola; Kudryavtsev, Alexander V (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-01)
      Associations between obesity and socio-demographic and behavioral characteristics vary between populations. Exploring such differences should throw light on factors related to obesity. We examined associations between general obesity (GO, defined by body mass index) and abdominal obesity (AO, defined by waist-to-hip ratio) and sex, age, socio-economic characteristics (education, financial ...
    • Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway 

      Cook, Sarah Anne; Hopstock, Laila Arnesdatter; Eggen, Anne Elise; Bates, Katie; Iakunchykova, Olena; Kontsevaya, Anna; McKee, Martin; Schirmer, Henrik; Voevoda, Michael; Kudryavtsev, Alexander V; Malyutina, Sofia; Leon, David A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-19)
      <i>Background</i> - Cardiovascular disease (CVD) mortality is substantially higher in Russia than in neighbouring Norway. We aimed to compare blood pressure- and lipid-lowering medication use and proportion meeting treatment targets between general population samples in the two countries in those with CVD and diabetes.<p><p> <i>Methods</i> - The study population was adults aged 40–69 years reporting ...
    • Prevalence of symptoms, ever having received a diagnosis and treatment of depression and anxiety, and associations with health service use amongst the general population in two Russian cities 

      Cook, Sarah Anne; Kudryavtsev, Alexander V; Bobrova, Natalia; Saburova, Lyudmila; Denisova, Diana; Malyutina, Sofia; Lewis, Glyn; Leon, David A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-12)
      <i>Background</i> - Little is known about the burden of common mental disorders in Russia despite high levels of suicide and alcohol-related mortality. Here we investigated levels of symptoms, self-reports of ever having received a diagnosis and treatment of anxiety and depression in two Russian cities.<p> <p><i>Methods</i> - The study population was men and women aged 35–69 years old participating ...
    • Primary care use and cardiovascular disease risk in Russian 40–69 year olds: a cross-sectional study 

      Petersen, Jakob; Kontsevaya, Anna V.; McKee, Martin; Richardson, E.; Cook, Sarah Anne; Malyutina, Sofia; Kudryavtsev, Alexander V; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-04)
      <i>Background</i> - The Russian Federation has very high cardiovascular disease (CVD) mortality rates compared with countries of similar economic development. This cross-sectional study compares the characteristics of CVD-free participants with and without recent primary care contact to ascertain their CVD risk and health status.<br><br> <i>Methods</i> - A total of 2774 participants aged 40–69 ...